I enjoy blues myself and this is what I do. I play a Godin exit 22-s equipped with ssh pickups with a crybaby wah Gcb95. I modded it for a slight mid boost which also makes the heel/toe transition not so drastic and also put in a vocal mod which makes it more like a human voice (these are easy 1 resistor each replacements). Don't get to heavy with the pedal, alittle rocking gives you that floaty SRV, live Clapton feel. I play through a stock 1973 Fender Vibro champ 6watt amp. Stay off the bridge pickup and try picking way up near or over the bottom of the neck. Then play with amps tone settings and add alittle reverb. Hope this gets ya closer to what moves ya.