Yep, I've run into this with most every electronic tuner regarding that particular string anyways. No big deal though...just tune the rest of them as accurately as you can, then tune the E to those, either by fretting or using harmonics. Otherwise, you can tune to a cd whose key you know. And there's also a quite a few sites online that have audible tones/samples for tuning, but I'll leave it to you (or others) to dig em up.
[FONT=Palatino Linotype]"Bust a nut!" - Dimebag
"Imagination is more important than knowledge." - Einstein[/FONT]