I play heavy instrumentals with a bit of shred. Here's my setup:

Guitars...................................................................
Ibanez 'Bad Horsie' Jem - Dimarzio Breeds
Ibanez Prestige custom - EMG 81/85
Ernie Ball Music Man 7 string Petrucci sig (custom JP Dimarzio's)
Gibson Les Paul Cusotm Historic '57 Goldtop reissue (burstbuckers)

Rack mounted gear...................................................
BOSS GT-Pro (distortions/modellers/effects)
Mesa Boogie Triaxis V2 (tube distortion preamp)
Mesa Boogie Simul Class 2:90 (tube power amp)
Eventide Harmonizer H3000 D/SE (effects processor)
ISP Decimator (noise reduction)
Palmer PDI-03 (speaker simulator)
Yamaha SPX1000 (effects processor)

Misc......................................................................
PODxt
Line6 DM4
Boss Line Switcher

Amp......................................................................
Marshall 100DFX (amp)

Recording/mixing (striaght from rack gear)....................
Mackie HUI (DAW controler)
M-Audio Delta 1010 (rack mounted sound card)
Dell Optiplex custom built (pc - too much spec for here!)
Cubase SX3 (recording/arranging)
Halion 3 (sampler)
Storm Drum (drums)
DFH Superior (drums)
Tannoy Reveals (studio monitors)
Sennheiser Pro Mixing headphones

That's it..... for now!